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3rd PartyASHP Injectable Drug Information
ASHP Injectable Drug Information
This package has 1 module with a total of 417 entries.
ASHP Injectable Drug Information Module
This package contains comprehensive guides to intravenous drug compatibility and stability.
ASHP Injectable Drug Information Sample Monograph
<?xml version='1.0' encoding='UTF-8'?>
<!DOCTYPE dif SYSTEM "dif.dtd">
<dif extraction-date='20211201'>
<hid>
<!-- **********************************************************************
All material distributed as part of ASHP Injectable Drug Information is copyrighted.
Reproduction, storage on a retrieval system, or transmission of this material
or any part thereof in any form or by any means without the express written
permission of the American Society of Health-System Pharmacists is
prohibited.
Please contact ASHP Office of Publications at +1 (301) 657-3000
for more detailed information.
(c) Copyright, 2021, American Society of Health-System
Pharmacists, Inc. All Rights Reserved.
********************************************************************** -->
<hid-mono unit-id='a582208' cpyrt-date='19821001' cx-date='20211102' mono-type='mono'>
<unit-num>
582208
</unit-num>
<intro-info>
<print-class>
<class-num class-code-ref='8:12.28.16' class-text='Glycopeptides'/>
</print-class>
<print-title>
Vancomycin Hydrochloride
</print-title>
<full-title>
Vancomycin Hydrochloride
</full-title>
<drug-name-info>
<gen-name>
Vancomycin Hydrochloride
</gen-name>
<cas-num>
1404-93-9
</cas-num>
</drug-name-info>
</intro-info>
<products>
<head class='a-head'>
Products
</head>
<para>
Vancomycin hydrochloride is available in single-dose vials containing drug equivalent to 250 mg, 500 mg, 750
mg, 1 g, 1.25 g, and 1.5 g of vancomycin base, and pharmacy bulk packages containing drug equivalent to 5, 10,
and 100 g of vancomycin base.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
To reconstitute single-use vials, 5 mL of sterile water for injection should be added for each 250 mg of
vancomycin lyophilized powder contained in the vial (e.g., add 15 mL of sterile water to reconstitute a 750-mg
vial of vancomycin) to yield a solution with a vancomycin concentration of 50 mg/mL.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
Pharmacy bulk packages containing 5 g of vancomycin should be reconstituted with 100 mL of sterile water for
injection to yield a solution with a vancomycin concentration of 50 mg/mL.
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
Pharmacy bulk packages containing 10 or 100 g of vancomycin should be reconstituted with 95 or 950 mL,
respectively, of sterile water for injection to yield a solution with a vancomycin concentration of 100 mg/mL.
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
The appropriate dose of the reconstituted solution prepared from single-dose vials must be further diluted in
a compatible diluent to achieve a final vancomycin concentration of 5 mg/mL (e.g., 500 mg in at least 100 mL,
750 mg in at least 150 mL, 1 g in at least 200 mL).
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
The appropriate dose of the reconstituted solution prepared from pharmacy bulk packages must be further
diluted in at least 100 mL of a compatible diluent;
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
some manufacturers state that doses of 1 g must be diluted in at least 200 mL of a compatible diluent.
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
Manufacturers state that vancomycin concentrations of no more than 5 mg/mL are recommended in adults.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
More concentrated vancomycin solutions (i.e., up to 10 mg/mL) may be considered for use in selected patients
(e.g., fluid-restricted patients); however, use of such solutions increases the risk of infusion-related
adverse effects.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride is available in ADD-Vantage vials containing drug equivalent to 500 mg, 750 mg, and 1
g of vancomycin base.
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
ADD-Vantage vials containing 500 mg of vancomycin should be prepared with
<ital>
at least
</ital>
100 mL of dextrose 5% or sodium chloride 0.9% in ADD-Vantage diluent bags; ADD-Vantage vials containing 750
mg or 1 g of vancomycin should be prepared
<ital>
only
</ital>
with 250 mL of dextrose 5% or sodium chloride 0.9% in ADD-Vantage diluent bags.
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
The manufacturer states that the use of ADD-Vantage vials is indicated only when doses reflecting the full
strength of the available products are determined to be appropriate; if vancomycin doses of 500 mg, 750 mg, or
1 g are not appropriate (e.g., in neonates, infants, and pediatric patients requiring doses less than 500 mg),
conventional vials of vancomycin hydrochloride should be used.
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride also is available in several ready-to-use formulations.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
Vancomycin hydrochloride is available as a frozen iso-osmotic premixed injection in single-dose Galaxy
containers containing the equivalent of 500 mg, 750 mg, and 1 g of vancomycin base in 100, 150, and 200 mL,
respectively, of dextrose 5% or sodium chloride 0.9%.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Each 100 mL of the premixed solution also contains either 5 g of dextrose hydrous or 0.9 g of sodium
chloride, and the pH may have been adjusted with hydrochloric acid and/or sodium hydroxide.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Vancomycin hydrochloride is available as a premixed injection in single-dose bags containing the equivalent
of 500 mg, 1 g, 1.5 g, and 2 g of vancomycin base in 100, 200, 300, and 400 mL, respectively.
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
Each 100 mL of the premixed solution also contains polyethylene glycol (PEG) 400 1.8 mL,
<ital>
N
</ital>
-acetyl-
<smcaps>
d
</smcaps>
-alanine (NADA) 1.36 g, and
<smcaps>
l
</smcaps>
-lysine hydrochloride (monochloride) 1.26 g in water for injection; hydrochloric acid and sodium hydroxide are
used for pH adjustment.
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
The PEG- and NADA-containing formulation should
<ital>
not
</ital>
be used in certain patients (e.g., pregnant women, patients younger than 1 month of age, pediatric patients 1
month of age or older requiring less than the entire dose of a single-dose flexible bag).
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
</para>
<sect>
<head class='b-head'>
pH
</head>
<para>
A 50- or 100-mg/mL reconstituted solution of vancomycin prepared with sterile water for injection has a pH
ranging from 2.5 to 4.5.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
</para>
<para>
Premixed infusion solutions of vancomycin (Baxter) 5 mg/mL in dextrose 5% or sodium chloride 0.9% have a pH
ranging from 3 to 5.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
</para>
<para>
Premixed infusion solutions of vancomycin (Xellia) 5 mg/mL have a pH ranging from 4.5 to 5.5.
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Osmolality
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 50 mg/mL in sterile water for
injection has an osmolality of 57 mOsm/kg.
<sup>
<a href='a586999.xml#r50'>
50
</a>
</sup>
</para>
<para>
The osmolality of vancomycin hydrochloride (Lederle) prepared at a vancomycin concentration of 5 mg/mL was
determined to be 249 mOsm/kg in dextrose 5% and 291 mOsm/kg in sodium chloride 0.9%.
<sup>
<a href='a586999.xml#r1375'>
1375
</a>
</sup>
</para>
<para>
The osmolality of vancomycin hydrochloride (Sandoz) prepared at a vancomycin concentration of 62.5 mg/mL was
determined to be 363 to 383 mOsm/kg in dextrose 5% and 337 to 351 mOsm/kg in sodium chloride 0.9%.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
The osmolality of vancomycin hydrochloride (Sandoz) prepared at a vancomycin concentration of 83.3 mg/mL
was determined to be 379 to 409 mOsm/kg in dextrose 5% and 362 to 378 mOsm/kg in sodium chloride 0.9%.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Osmolarity
</head>
<para>
The osmolarity of premixed infusion solutions of vancomycin (Xellia) 5 mg/mL ranges from 350 to 475
mOsmol/L.
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
</para>
</sect>
</products>
<administration>
<head class='a-head'>
Administration
</head>
<para>
Vancomycin hydrochloride is administered by intravenous infusion.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
The reconstituted solution must be diluted in a compatible infusion solution prior to administration.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
The drug is extremely irritating to tissue and may cause necrosis; therefore, it should not be given by
intramuscular injection and extravasation should be avoided during intravenous administration.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
The frequency and severity of thrombophlebitis can be minimized by administering the drug slowly, using
dilute solutions of 2.5 to 5 mg/mL, and rotating venous access sites.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
</para>
<para>
Manufacturers recommend intermittent intravenous infusion as the preferred method of administration.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
Some manufacturers recommend that the drug be administered over a period of at least 60 minutes in adults.
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
Other manufacturers state that administration rates of no more than 10 mg/min are recommended in adults or
that the drug should be administered at a rate no faster than 10 mg/min or over a period of at least 60
minutes, whichever is longer.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
In pediatric patients, the drug should be administered over a period of at least 60 minutes;
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
in neonates, the drug should be administered over a period of 60 minutes.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Baxter) frozen iso-osmotic premixed injection in single-dose Galaxy containers
should be thawed (see Stability: Freezing Solutions), and the solution should be administered by intravenous
infusion.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
</para>
</administration>
<stability>
<head class='a-head'>
Stability
</head>
<para>
Vancomycin hydrochloride is a lyophilized powder that varies in color from white or off white to light tan,
tan, buff, or brownish.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
Intact vials and pharmacy bulk packages should be stored at controlled room temperature.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
Manufacturers indicate that after reconstitution, single-dose vials of vancomycin hydrochloride may be stored
in a refrigerator for 14 days with no significant loss of potency;
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
other information has indicated that the drug also is stable in solution for 14 days at room temperature.
<sup>
<a href='a586999.xml#r141'>
141
</a>
</sup>
</para>
<para>
Intact ADD-Vantage vials of vancomycin hydrochloride should be stored at controlled room temperature.
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
Solutions prepared using the ADD-Vantage vials may be stored in a refrigerator 14 days for with no
significant loss of potency.
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
</para>
<sect>
<head class='b-head'>
pH Effects
</head>
<para>
In the pH range of 2 to 10, vancomycin hydrochloride degradation occurs principally via deamidation.
<sup>
<a href='a586999.xml#r1927'>
1927
</a>
</sup>
Vancomycin hydrochloride has been reported to be most stable at pH 3 to 5
<sup>
<a href='a586999.xml#r141'>
141
</a>
</sup>
and at pH 5.5,
<sup>
<a href='a586999.xml#r1927'>
1927
</a>
</sup>
with relatively pH-independent decomposition in the range of 3 to 8.
<sup>
<a href='a586999.xml#r1927'>
1927
</a>
</sup>
The stability of a 1-mg/mL concentration was evaluated in buffer solutions having pH values of 1.4, 5.6,
and 7.1 at 24°C. Little or no loss occurred in 24 hours in any solution. However, the pH 1.4 buffer had
a 19% loss in 5 days, the pH 5.6 buffer had a 10% loss in 17 days, and the pH 7.1 buffer had an 11% loss in
5 days.
<sup>
<a href='a586999.xml#r1134'>
1134
</a>
</sup>
</para>
<para>
In an accelerated study at 66°C, the half-life of vancomycin B (the largest component of the commercial
product) was 400 minutes in a phosphate buffer with a pH of 2.2 and 650 minutes in a phosphate buffer with a
pH of 7.
<sup>
<a href='a586999.xml#r1354'>
1354
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride has a low pH and may cause chemical or physical instability when mixed with other
drugs, especially drugs with an alkaline pH.
<sup>
<a href='a586999.xml#r873'>
873
</a>
</sup>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
<sup>
<a href='a586999.xml#r3471'>
3471
</a>
</sup>
<sup>
<a href='a586999.xml#r3472'>
3472
</a>
</sup>
</para>
<para>
The concentration dependency of compatibility or incompatibility of vancomycin hydrochloride mixed with or
administered simultaneously with a number of penicillins and cephalosporins has been demonstrated.
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
Vancomycin hydrochloride is variably compatible with drugs having neutral to mildly alkaline pH, including
cephalosporins and penicillins. The compatibility may depend on a number of factors including concentration
of each drug, dilution vehicle, actual pH of solutions, and completeness of mixing during administration.
Combinations that are compatible when well mixed may result in precipitation if only partially mixed,
presumably due to regionally different concentrations and pH values. If attempting to administer vancomycin
hydrochloride with another drug product, care should be taken to ensure that the specific combination and
concentrations are compatible under the exact administration conditions to be used. An inline filter should
be used as a final safety measure.
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Freezing Solutions
</head>
<para>
The commercially available, premixed frozen injection of vancomycin hydrochloride in single-dose Galaxy
containers should be stored in a freezer capable of maintaining the temperature at or below -20°C.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Frozen product containers should be handled with care since they may be fragile in the frozen state.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Freezing of the solution may cause components of the solution to precipitate, but this precipitate will
dissolve at room temperature, apparently without affecting potency.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Solutions should be thawed at room temperature (25°C) or under refrigeration (5°C).
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Solutions should not be subject to force thawing (e.g., by immersion in water baths or microwaving).
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
Thawed solutions should not be refrozen.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
After the thawed solution has reached room temperature, the solution should be agitated.
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
The manufacturer indicates that thawed solutions remain chemically stable for 72 hours at room temperature
(25°C) or 30 days refrigerated (5°C).
<sup>
<a href='a586999.xml#r3470'>
3470
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 5 mg/mL in dextrose 5% or sodium
chloride 0.9% exhibited no loss after 63 days of storage when frozen at -10°C. However, neither did a
loss occur in the same time period when the solution was stored at 5°C.
<sup>
<a href='a586999.xml#r1134'>
1134
</a>
</sup>
</para>
<para>
In one study, vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 5 mg/mL in dextrose
5% was stored frozen at -20°C for 105 days. After thawing in a microwave, the samples were stored for
56 more days under refrigeration. The samples remained clear and had no color change. In addition, no loss
of vancomycin occurred throughout the entire test period.
<sup>
<a href='a586999.xml#r2682'>
2682
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Syringes
</head>
<para>
The stability of vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 5 mg/mL in
dextrose concentrations ranging from 5 to 30% and packaged in plastic syringes was studied. The syringes
were stored at 4°C for 24 hours followed by 2 hours at room temperature. Little change in the
concentration occurred.
<sup>
<a href='a586999.xml#r1301'>
1301
</a>
</sup>
</para>
<para>
The stability of vancomycin hydrochloride (Lilly) reconstituted to a vancomycin concentration of 10 mg/mL
with sterile water for injection, dextrose 5%, and sodium chloride 0.9% repackaged into plastic syringes was
studied. Five mL of the solutions were filled into 3-piece Plastipak (Becton Dickinson) and 2-piece Injekt
(Braun) syringes that were then sealed with Luer-Lok hubs (Vigon) and stored at 4 and 25°C for 84 days.
Under refrigeration, vancomycin hydrochloride prepared with all 3 solutions and packaged in both kinds of
syringes was physically and chemically stable for the 84-day period; losses were 4% or less.
<sup>
<a href='a586999.xml#r1893'>
1893
</a>
</sup>
However, stored at 25°C in the Plastipak syringes, 10% loss occurred in about 47 days in water, 55
days in dextrose 5%, and 62 days in sodium chloride 0.9%. In the Injekt syringes, stability was less; 10%
loss occurred in 29 days in water, 33 days in dextrose 5%, and 34 days in sodium chloride 0.9%. In addition,
a degradation product appeared as a white flocculent precipitate in all room temperature samples after about
8 weeks of storage.
<sup>
<a href='a586999.xml#r1893'>
1893
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride prepared at a vancomycin concentration of 5 mg/mL in dextrose 5% and in sodium
chloride 0.9% packaged in polypropylene syringes (Becton Dickinson) exhibited less than 10% loss in 14 days
at room temperature and in 6 months under refrigeration. Refrigerated solutions warmed to room temperature
were stable for 48 hours.
<sup>
<a href='a586999.xml#r2730'>
2730
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Mylan) prepared at a vancomycin concentration of 2 g/48 mL in dextrose 5% and in
sodium chloride 0.9% packaged in polypropylene syringes (Terumo) was physically and chemically stable for up
to 48 hours at an ambient temperature ranging from 18 to 25°C.
<sup>
<a href='a586999.xml#r3602'>
3602
</a>
</sup>
</para>
<para>
No visual or subvisual changes were noted in polypropylene syringes containing vancomycin hydrochloride
prepared at vancomycin concentrations of 40, 50, 58.8, 71, and 83.3 mg/mL in sodium chloride 0.9% in 24
hours at room temperature and 83.3 mg/mL in both sodium chloride 0.9% and dextrose 5% in 48 hours at room
temperature.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Sandoz) prepared at a vancomycin concentration of 3 g/48 mL in dextrose 5% and
packaged in 50-mL polypropylene Plastipak (Becton Dickinson) syringes exhibited little loss in 24 hours at
20 to 25°C with no degradation products, change in pH, or visible modifications noted.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
Syringes prepared at a vancomycin concentration of 4 g/48 mL in dextrose 5% exhibited a slight yellow color
change and little loss in 6 hours at 20 to 25°C.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
While the concentration of vancomycin in one of the 3 syringes (tested in triplicate) dropped below 90% of
the initial concentration at 24 hours, the concentration in that syringe measured well above 90% of the
initial concentration at 48 hours.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
Authors attributed these results to a technical problem likely related to the multiple dilutions required
to achieve the desired theoretical concentration of the drug and concluded that the drug was physically and
chemically stable for 48 hours at 20 to 25°C.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Sandoz) prepared at a vancomycin concentration of 3 g/48 mL in sodium chloride
0.9% and packaged in 50-mL polypropylene Plastipak (Becton Dickinson) syringes exhibited little loss in 48
hours at 20 to 25°C without any physical changes noted.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
Syringes prepared at a vancomycin concentration of 4 g/48 mL in sodium chloride 0.9% exhibited little loss
in 24 hours at 20 to 25°C, but a precipitate was observed after 48 hours of storage.
<sup>
<a href='a586999.xml#r3603'>
3603
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Elastomeric Reservoir Pumps
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 10 mg/mL in both dextrose 5% and
sodium chloride 0.9% was evaluated for binding potential to natural rubber elastomeric reservoirs (Baxter).
No binding was found after storage for 2 weeks at 35°C with gentle agitation.
<sup>
<a href='a586999.xml#r2014'>
2014
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Implantable Pumps
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 1 mg/mL in water in an
implantable pump (Infusaid model 100) was incubated in a water bath at 37°C for 28 days. Vancomycin
losses were substantial, with about 25% loss in 7 days and 40% loss in 28 days. At the end of the test
period, a colloidal precipitate also was found in the pumps.
<sup>
<a href='a586999.xml#r1302'>
1302
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Sorption
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 15 mg/mL in dextrose 5% is
reported to undergo substantial sorption to Teflon tubing used in an automatic dilutor (Syva). The
vancomycin hydrochloride was apparently released from the tubing into subsequent solutions resulting in
vancomycin toxicity.
<sup>
<a href='a586999.xml#r2153'>
2153
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride prepared at a vancomycin concentration of 10 mg/mL with heparin sodium 5000
units/mL as an antibiotic lock in polyurethane central hemodialysis catheters lost about 50% of the
antibiotic over 72 hours at 37°C. The loss was attributed to sorption to the catheters, although
precipitation is also possible. Nevertheless, the reduced antibiotic concentration (about 5 mg/mL) remained
effective against common microorganisms in catheter-related bacteremia in hemodialysis patients.
<sup>
<a href='a586999.xml#r2515'>
2515
</a>
</sup>
<sup>
<a href='a586999.xml#r2516'>
2516
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Plasticizer Leaching
</head>
<para>
Vancomycin hydrochloride (Qualimed Laboratories) prepared at a vancomycin concentration of 8 mg/mL in
dextrose 5% and sodium chloride 0.9% in polyvinyl chloride (PVC) containers (Macropharma) did not leach
detectable amounts of diethylhexyl phthalate (DEHP) plasticizer during simulated administration over 24
hours. If any DEHP was present, the concentration was less than 1 mcg/mL, the limit of detection in this
study.
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Filtration
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 2 mg/mL in dextrose 5% or sodium
chloride 0.9% was filtered through a 0.22-μm cellulose ester filter (Ivex-HP, Millipore) over 6 hours.
No significant drug loss due to binding to the filter was noted.
<sup>
<a href='a586999.xml#r1034'>
1034
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Central Venous Catheter
</head>
<para>
Vancomycin hydrochloride (Fujisawa) prepared at a vancomycin concentration of 2 mg/mL in dextrose 5% was
found to be compatible with the ARROWg+ard Blue Plus (Arrow International) chlorhexidine-bearing
triple-lumen central catheter. Essentially complete delivery of the drug was found with little or no drug
loss occurring. Furthermore, chlorhexidine delivered from the catheter remained at trace amounts with no
substantial increase due to the delivery of the drug through the catheter.
<sup>
<a href='a586999.xml#r2335'>
2335
</a>
</sup>
</para>
</sect>
</stability>
<compatibility>
<head class='a-head'>
Compatibility Information
</head>
<solution-compat>
<head class='b-head'>
Solution Compatibility
</head>
<table frame='topbot'>
<head>
Vancomycin HCl
</head>
<tgroup cols='7' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='2*'/>
<colspec colnum='2' colname='col2' colwidth='1*'/>
<colspec colnum='3' colname='col3' colwidth='1*'/>
<colspec colnum='4' colname='col4' colwidth='1*'/>
<colspec colnum='5' colname='col5' colwidth='3*'/>
<colspec colnum='6' colname='col6' colwidth='1*'/>
<colspec colnum='7' colname='col7' colwidth='1*'/>
<thead>
<row rowsep='1' valign='bottom'>
<entry colname='col1'>
<para>
Test Soln Name
</para>
</entry>
<entry colname='col2'>
<para>
Test Soln Mfr
</para>
</entry>
<entry colname='col3'>
<para>
Base Drug Mfr
</para>
</entry>
<entry colname='col4'>
<para>
Base Drug Conc/L or %
</para>
</entry>
<entry colname='col5'>
<para>
Remarks
</para>
</entry>
<entry colname='col6'>
<para>
Refs
</para>
</entry>
<entry colname='col7'>
<para>
Compat
</para>
</entry>
</row>
</thead>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5% in Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5% in Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5% in sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5% in sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5% in sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
1 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 14 days refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 14 days refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
1 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Stable for 7 days at 5 and 25°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r141'>
141
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
TR
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible and stability for 24 hr at room temperature
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r518'>
518
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
TR
<a href='#sol-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible with no loss in 7 days and 5% loss in 17 days at 24°C. In glass
containers, no loss in 63 days at 5°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1134'>
1134
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
TR
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
4 and 5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible with 8% loss in 17 days at 23°C and 11% loss in 30 days at 4°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1354'>
1354
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
AB
<a href='#sol-f5'>
<sup>
e
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
AB
</para>
</entry>
<entry colname='col4'>
<para>
20 and 40 g
</para>
</entry>
<entry colname='col5'>
<para>
Little loss in 96 hr at 25°C and in 30 days at 5°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2097'>
2097
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
8 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during a 24 hr simulated infusion at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during a 1 hr simulated infusion at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during storage for 48 hr at 22°C in light and 7 days at
4°C in dark
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 and 10 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible with less than 3% loss in 58 days at 4°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2252'>
2252
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f6'>
<sup>
f
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
2 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible with no loss at 4°C and 4 to 6% loss at room temperature in 48 hr
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2278'>
2278
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f7'>
<sup>
g
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
HOS
</para>
</entry>
<entry colname='col4'>
<para>
1 and 5 g
</para>
</entry>
<entry colname='col5'>
<para>
Under 10% loss in 7 days at 23°C and 31 days at 4°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2819'>
2819
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f8'>
<sup>
h
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
GSK
</para>
</entry>
<entry colname='col4'>
<para>
10 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically and chemically stable for 23 days at 2 to 8°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3479'>
3479
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f8'>
<sup>
h
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
10 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically and chemically stable for 43 days at 2 to 8°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3479'>
3479
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dextrose 10%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r143'>
143
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Isolyte E
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Normosol M in dextrose 5%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Normosol R
</para>
</entry>
<entry colname='col2'>
<para>
HOS
</para>
</entry>
<entry colname='col3'>
<para>
FRK
<a href='#sol-f9'>
<sup>
i
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible for 4 hr at 21°C in the dark during simulated Y-site administration
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3719'>
3719
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 96 hr refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r143'>
143
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ringer’s injection, lactated
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
1 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
FRK, HOS
</para>
</entry>
<entry colname='col4'>
<para>
4 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 14 days refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
MYL
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
May be stored for 14 days refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Stable for at least 7 days at 5 and 25°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r141'>
141
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
1 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
TR
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible and stable for 24 hr at room temperature
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r518'>
518
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
TR
<a href='#sol-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible with no loss in 7 days and 5% loss in 17 days at 24°C. In glass
containers, no loss in 63 days at 5°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1134'>
1134
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
TR
</para>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
4 and 5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible with 9% loss in 24 days at 23°C and 5 to 6% loss in 30 days at 4°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1354'>
1354
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
AB
<a href='#sol-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
ES
</para>
</entry>
<entry colname='col4'>
<para>
10 g
</para>
</entry>
<entry colname='col5'>
<para>
Little loss with 24-hr storage at 5°C followed by 24-hr simulated administration at 30°C
via portable pump
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1779'>
1779
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
8 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during a 24 hr simulated infusion at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during a 1 hr simulated infusion at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and no loss during storage for 48 hr at 22°C in light and 7 days at
4°C in dark
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2148'>
2148
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#sol-f6'>
<sup>
f
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
QLM
</para>
</entry>
<entry colname='col4'>
<para>
2 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible with no loss at 4°C and at room temperature in 48 hr
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2278'>
2278
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium chloride 0.9%
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#sol-f7'>
<sup>
g
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
HOS
</para>
</entry>
<entry colname='col4'>
<para>
1 and 5 g
</para>
</entry>
<entry colname='col5'>
<para>
Under 10% loss in 7 days at 23°C and 31 days at 4°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r2819'>
2819
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium lactate (1/6) M
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
5 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r143'>
143
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #95, #96
<a href='#sol-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LE
</para>
</entry>
<entry colname='col4'>
<para>
400 mg
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible and no vancomycin loss for 8 days at room temperature and refrigerated
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1321'>
1321
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #105, #106
<a href='#sol-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
1 and 6 g
</para>
</entry>
<entry colname='col5'>
<para>
Physically compatible with little or no vancomycin loss in 4 hr at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1325'>
1325
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #107
<a href='#sol-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para/>
</entry>
<entry colname='col4'>
<para>
200 mg
</para>
</entry>
<entry colname='col5'>
<para>
Activity retained for 24 hr at 21°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1326'>
1326
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #202
<a href='#sol-f1'>
<sup>
a
</sup>
</a>
<a href='#sol-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
LI
</para>
</entry>
<entry colname='col4'>
<para>
500 mg and 1 g
</para>
</entry>
<entry colname='col5'>
<para>
Visually compatible and activity retained for 35 days at 4°C plus 24 hr at 22°C
</para>
</entry>
<entry colname='col6'>
<para>
<sup>
<a href='a586999.xml#r1933'>
1933
</a>
</sup>
</para>
</entry>
<entry colname='col7'>
<para>
C
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
<table frame='bottom'>
<tgroup cols='1' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='*'/>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
<a name='sol-f1'/>
<sup>
a
</sup>
Tested in PVC containers.
</para>
<para>
<a name='sol-f2'/>
<sup>
b
</sup>
Tested in both glass and PVC containers.
</para>
<para>
<a name='sol-f3'/>
<sup>
c
</sup>
Tested in portable pump reservoirs (Pharmacia Deltec).
</para>
<para>
<a name='sol-f4'/>
<sup>
d
</sup>
Refer to Appendix for the composition of parenteral nutrition solutions. TPN indicates a 2-in-1
admixture.
</para>
<para>
<a name='sol-f5'/>
<sup>
e
</sup>
Tested in SIMS Deltec Medication Cassette reservoirs.
</para>
<para>
<a name='sol-f6'/>
<sup>
f
</sup>
Tested in PVC, polyolefin, and glass containers.
</para>
<para>
<a name='sol-f7'/>
<sup>
g
</sup>
Tested in Accufusor reservoirs.
</para>
<para>
<a name='sol-f8'/>
<sup>
h
</sup>
Tested in polyolefin containers.
</para>
<para>
<a name='sol-f9'/>
<sup>
i
</sup>
Tested in sodium chloride 0.9%.
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
</solution-compat>
<additive-compat>
<head class='b-head'>
Additive Compatibility
</head>
<table frame='topbot'>
<head>
Vancomycin HCl
</head>
<tgroup cols='9' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='2*'/>
<colspec colnum='2' colname='col2' colwidth='1*'/>
<colspec colnum='3' colname='col3' colwidth='1*'/>
<colspec colnum='4' colname='col4' colwidth='1*'/>
<colspec colnum='5' colname='col5' colwidth='1*'/>
<colspec colnum='6' colname='col6' colwidth='1*'/>
<colspec colnum='7' colname='col7' colwidth='3*'/>
<colspec colnum='8' colname='col8' colwidth='1*'/>
<colspec colnum='9' colname='col9' colwidth='1*'/>
<thead>
<row rowsep='1' valign='bottom'>
<entry colname='col1'>
<para>
Test Drug
</para>
</entry>
<entry colname='col2'>
<para>
Test Drug Mfr
</para>
</entry>
<entry colname='col3'>
<para>
Test Drug Conc/L or %
</para>
</entry>
<entry colname='col4'>
<para>
Base Drug Mfr
</para>
</entry>
<entry colname='col5'>
<para>
Base Drug Conc/L or %
</para>
</entry>
<entry colname='col6'>
<para>
Test Solution
</para>
</entry>
<entry colname='col7'>
<para>
Remarks
</para>
</entry>
<entry colname='col8'>
<para>
Refs
</para>
</entry>
<entry colname='col9'>
<para>
Compat
</para>
</entry>
</row>
</thead>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
Amikacin sulfate
</para>
</entry>
<entry colname='col2'>
<para>
BR
</para>
</entry>
<entry colname='col3'>
<para>
5 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
2 g
</para>
</entry>
<entry colname='col6'>
<para>
D5LR, D5R, D5S, D5W, D10W, LR, NS, R, SL
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible and amikacin stable for 24 hr at 25°C. Vancomycin not tested
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r293'>
293
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aminophylline
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
250 mg
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aminophylline
</para>
</entry>
<entry colname='col2'>
<para>
SE
</para>
</entry>
<entry colname='col3'>
<para>
1 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r15'>
15
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Atracurium besylate
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
500 mg
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible and atracurium stable for 24 hr at 5 and 30°C
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1694'>
1694
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aztreonam
</para>
</entry>
<entry colname='col2'>
<para>
SQ
</para>
</entry>
<entry colname='col3'>
<para>
40 g
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W, NS
</para>
</entry>
<entry colname='col7'>
<para>
Immediate microcrystalline precipitate. Turbidity and precipitate over 24 hr
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1848'>
1848
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aztreonam
</para>
</entry>
<entry colname='col2'>
<para>
SQ
</para>
</entry>
<entry colname='col3'>
<para>
4 g
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible. Little loss of either drug in 31 days at 4°C. 10% aztreonam loss in 14
days at 23°C and 7 days at 32°C
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1848'>
1848
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aztreonam
</para>
</entry>
<entry colname='col2'>
<para>
SQ
</para>
</entry>
<entry colname='col3'>
<para>
4 g
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
NS
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible. Little loss of either drug in 31 days at 4°C. 8% aztreonam loss in 31
days at 23°C and 7 days at 32°C
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1848'>
1848
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Calcium gluconate
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
1 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
BR
</para>
</entry>
<entry colname='col3'>
<para>
4 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W, NS
</para>
</entry>
<entry colname='col7'>
<para>
4% cefepime loss in 24 hr at room temperature in light and 2% loss in 7 days at 5°C. No
vancomycin loss. Cloudiness in 5 days at 5°C
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1682'>
1682
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
BR
</para>
</entry>
<entry colname='col3'>
<para>
40 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W, NS
</para>
</entry>
<entry colname='col7'>
<para>
4% cefepime loss in 24 hr at room temperature in light and 2% loss in 7 days at 5°C. No
vancomycin loss and no cloudiness
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1682'>
1682
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Chloramphenicol sodium succinate
</para>
</entry>
<entry colname='col2'>
<para>
PD
</para>
</entry>
<entry colname='col3'>
<para>
10 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r15'>
15
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dimenhydrinate
</para>
</entry>
<entry colname='col2'>
<para>
SE
</para>
</entry>
<entry colname='col3'>
<para>
50 mg
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Famotidine
</para>
</entry>
<entry colname='col2'>
<para>
YAM
</para>
</entry>
<entry colname='col3'>
<para>
200 mg
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
<a href='#add-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col7'>
<para>
Visually compatible. 9% vancomycin and 6% famotidine loss in 14 days at 25°C. At 4°C, 4%
loss of both drugs in 14 days
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r2111'>
2111
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Fusidate sodium
</para>
</entry>
<entry colname='col2'>
<para>
LEO
</para>
</entry>
<entry colname='col3'>
<para>
500 mg
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
25 g
</para>
</entry>
<entry colname='col6'>
<para>
D2.5½S, D2.5S, D5¼S, D5½S, D5S, D10S
</para>
</entry>
<entry colname='col7'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1800'>
1800
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
12,000 units
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
IX
</para>
</entry>
<entry colname='col3'>
<para>
1000 units
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
400 mg
</para>
</entry>
<entry colname='col6'>
<para>
TPN #95
<a href='#add-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible and vancomycin stable for 8 days at room temperature and under refrigeration
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1321'>
1321
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ES
</para>
</entry>
<entry colname='col3'>
<para>
100,000 units
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
25 mg
</para>
</entry>
<entry colname='col6'>
<para>
NS
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible. Under 10% vancomycin loss and no heparin loss in 30 days at 28°C and
63 days at 4°C
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r2542'>
2542
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Hydrocortisone sodium succinate
</para>
</entry>
<entry colname='col2'>
<para>
UP
</para>
</entry>
<entry colname='col3'>
<para>
100 mg
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Meropenem
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
1 and 20 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
NS
</para>
</entry>
<entry colname='col7'>
<para>
Visually compatible for 4 hr at room temperature
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1994'>
1994
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
SZ
<a href='#add-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
8.6
<a href='#add-f3'>
<sup>
c
</sup>
</a>
g
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
2.9 g
</para>
</entry>
<entry colname='col6'>
<para>
NS
</para>
</entry>
<entry colname='col7'>
<para>
Visually compatible for up to 5 days at room temperature
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r2935'>
2935
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APO
<a href='#add-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
11.4
<a href='#add-f3'>
<sup>
c
</sup>
</a>
g
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
2.9 g
</para>
</entry>
<entry colname='col6'>
<para>
NS
</para>
</entry>
<entry colname='col7'>
<para>
Visually compatible for up to 5 days at room temperature
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r2935'>
2935
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Potassium chloride
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
3 g
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r74'>
74
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ranitidine HCl
</para>
</entry>
<entry colname='col2'>
<para>
GL
</para>
</entry>
<entry colname='col3'>
<para>
100 mg
</para>
</entry>
<entry colname='col4'>
<para>
DI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible for 24 hr at ambient temperature in light
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1151'>
1151
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ranitidine HCl
</para>
</entry>
<entry colname='col2'>
<para>
GL
</para>
</entry>
<entry colname='col3'>
<para>
50 mg and 2 g
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
5 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible. Ranitidine stable for 24 hr at 25°C. Vancomycin not tested
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r1515'>
1515
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Verapamil HCl
</para>
</entry>
<entry colname='col2'>
<para>
KN
</para>
</entry>
<entry colname='col3'>
<para>
80 mg
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
1 g
</para>
</entry>
<entry colname='col6'>
<para>
D5W, NS
</para>
</entry>
<entry colname='col7'>
<para>
Physically compatible for 24 hr
</para>
</entry>
<entry colname='col8'>
<para>
<sup>
<a href='a586999.xml#r764'>
764
</a>
</sup>
</para>
</entry>
<entry colname='col9'>
<para>
C
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
<table frame='bottom'>
<tgroup cols='1' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='*'/>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
<a name='add-f1'/>
<sup>
a
</sup>
Refer to Appendix for the composition of parenteral nutrition solutions. TPN indicates a 2-in-1
admixture.
</para>
<para>
<a name='add-f2'/>
<sup>
b
</sup>
Tested in methyl-methacrylate-butadiene-styrene plastic containers.
</para>
<para>
<a name='add-f3'/>
<sup>
c
</sup>
Piperacillin component. Piperacillin in an 8:1 fixed-ratio concentration with tazobactam.
</para>
<para>
<a name='add-f4'/>
<sup>
d
</sup>
Test performed using the formulation WITHOUT edetate disodium.
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
</additive-compat>
<drugs-in-syringe-compat>
<head class='b-head'>
Drugs in Syringe Compatibility
</head>
<table frame='topbot'>
<head>
Vancomycin HCl
</head>
<tgroup cols='8' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='2*'/>
<colspec colnum='2' colname='col2' colwidth='1*'/>
<colspec colnum='3' colname='col3' colwidth='1*'/>
<colspec colnum='4' colname='col4' colwidth='1*'/>
<colspec colnum='5' colname='col5' colwidth='1*'/>
<colspec colnum='6' colname='col6' colwidth='3*'/>
<colspec colnum='7' colname='col7' colwidth='1*'/>
<colspec colnum='8' colname='col8' colwidth='1*'/>
<thead>
<row rowsep='1' valign='bottom'>
<entry colname='col1'>
<para>
Test Drug
</para>
</entry>
<entry colname='col2'>
<para>
Test Drug Mfr
</para>
</entry>
<entry colname='col3'>
<para>
Test Drug Amt
</para>
</entry>
<entry colname='col4'>
<para>
Base Drug Mfr
</para>
</entry>
<entry colname='col5'>
<para>
Base Drug Amt
</para>
</entry>
<entry colname='col6'>
<para>
Remarks
</para>
</entry>
<entry colname='col7'>
<para>
Refs
</para>
</entry>
<entry colname='col8'>
<para>
Compat
</para>
</entry>
</row>
</thead>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
Caffeine citrate
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
20 mg/1 mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/1 mL
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2440'>
2440
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dimenhydrinate
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
10 mg/1 mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
50 mg/1 mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2569'>
2569
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
2500 units/1 mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
500 mg
</para>
</entry>
<entry colname='col6'>
<para>
Turbidity or precipitate forms within 5 min
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1053'>
1053
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Pantoprazole sodium
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#dru-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
4 mg/1 mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
50 mg/1 mL
</para>
</entry>
<entry colname='col6'>
<para>
Clear solution
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2574'>
2574
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
<table frame='bottom'>
<tgroup cols='1' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='*'/>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
<a name='dru-f1'/>
<sup>
a
</sup>
Test performed using the formulation WITHOUT edetate disodium.
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
</drugs-in-syringe-compat>
<y-site-inj-compat>
<head class='b-head'>
Y-Site Injection Compatibility (1:1 Mixture)
</head>
<table frame='topbot'>
<head>
Vancomycin HCl
</head>
<tgroup cols='8' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='2*'/>
<colspec colnum='2' colname='col2' colwidth='1*'/>
<colspec colnum='3' colname='col3' colwidth='1*'/>
<colspec colnum='4' colname='col4' colwidth='1*'/>
<colspec colnum='5' colname='col5' colwidth='1*'/>
<colspec colnum='6' colname='col6' colwidth='3*'/>
<colspec colnum='7' colname='col7' colwidth='1*'/>
<colspec colnum='8' colname='col8' colwidth='1*'/>
<thead>
<row rowsep='1' valign='bottom'>
<entry colname='col1'>
<para>
Test Drug
</para>
</entry>
<entry colname='col2'>
<para>
Test Drug Mfr
</para>
</entry>
<entry colname='col3'>
<para>
Test Drug Conc
</para>
</entry>
<entry colname='col4'>
<para>
Base Drug Mfr
</para>
</entry>
<entry colname='col5'>
<para>
Base Drug Conc
</para>
</entry>
<entry colname='col6'>
<para>
Remarks
</para>
</entry>
<entry colname='col7'>
<para>
Refs
</para>
</entry>
<entry colname='col8'>
<para>
Compat
</para>
</entry>
</row>
</thead>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
Acetaminophen
</para>
</entry>
<entry colname='col2'>
<para>
CAD
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible with little or no loss of either drug in 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2901'>
2901
</a>
</sup>
,
<sup>
<a href='a586999.xml#r2902'>
2902
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Acyclovir sodium
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1157'>
1157
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Albumin human
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
0.1 and 1%
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Heavy turbidity forms immediately and precipitate develops subsequently
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1701'>
1701
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aldesleukin
</para>
</entry>
<entry colname='col2'>
<para>
CHI
<a href='#y-si-f17'>
<sup>
q
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'/>
<entry colname='col6'>
<para>
Visually compatible. Aldesleukin activity retained. Vancomycin not tested
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1890'>
1890
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Allopurinol sodium
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
3 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LY
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1686'>
1686
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Alprostadil
</para>
</entry>
<entry colname='col2'>
<para>
BED
</para>
</entry>
<entry colname='col3'>
<para>
7.5 mcg/mL
<a href='#y-si-f16'>
<sup>
p
</sup>
</a>
<a href='#y-si-f5'>
<sup>
e
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f19'>
<sup>
s
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 1 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2746'>
2746
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Amifostine
</para>
</entry>
<entry colname='col2'>
<para>
USB
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1845'>
1845
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Amiodarone HCl
</para>
</entry>
<entry colname='col2'>
<para>
LZ
</para>
</entry>
<entry colname='col3'>
<para>
4 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1444'>
1444
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Amiodarone HCl
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
6 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2352'>
2352
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Amiodarone HCl
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
6 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2352'>
2352
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
250 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1, 10, 50 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 10
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 50
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 250
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium–sulbactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
PF
</para>
</entry>
<entry colname='col3'>
<para>
250 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium–sulbactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
PF
</para>
</entry>
<entry colname='col3'>
<para>
1, 10, 50 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ampicillin sodium–sulbactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
PF
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
, 10
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
, 50
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
, 250
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f20'>
<sup>
t
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Amsacrine
</para>
</entry>
<entry colname='col2'>
<para>
NCI
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1381'>
1381
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Anidulafungin
</para>
</entry>
<entry colname='col2'>
<para>
VIC
</para>
</entry>
<entry colname='col3'>
<para>
0.5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2617'>
2617
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Atracurium besylate
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
0.5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
ES
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 28°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1337'>
1337
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aztreonam
</para>
</entry>
<entry colname='col2'>
<para>
SQ
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
67 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White granular precipitate forms immediately in tubing when given sequentially
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1364'>
1364
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Aztreonam
</para>
</entry>
<entry colname='col2'>
<para>
SQ
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1758'>
1758
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Bivalirudin
</para>
</entry>
<entry colname='col2'>
<para>
TMC
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2373'>
2373
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cangrelor tetrasodium
</para>
</entry>
<entry colname='col2'>
<para>
TMC
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3243'>
3243
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Caspofungin acetate
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
0.7 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2758'>
2758
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Caspofungin acetate
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
0.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible over 60 min
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2766'>
2766
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
10 and 50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Subvisible haze forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefazolin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1 and 10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
BMS
</para>
</entry>
<entry colname='col3'>
<para>
120 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
30 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible with less than 10% cefepime loss. Vancomycin not tested
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2513'>
2513
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
APO
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
NVP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Samples from 4-hr cefepime and 1-hr vancomycin infusions physically compatible during infusion and
after 24 hr at 22.5°C in dark. Cefepime chemically stable during infusion and after 12 hr at
22.5°C in dark; vancomycin not measured using an assay noted to be stability indicating
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3475'>
3475
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
APO
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
NVP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Samples from 4-hr cefepime and 1-hr vancomycin infusions physically compatible during infusion and
after 24 hr at 22.5°C in dark. Cefepime chemically stable during infusion and after 12 hr at
22.5°C in dark; vancomycin not measured using an assay noted to be stability indicating
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3475'>
3475
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
APO
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
NVP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Samples from 4-hr cefepime and 1-hr vancomycin infusions physically compatible during infusion and
after 24 hr at 22.5°C in dark. Cefepime chemically stable during infusion and after 12 hr at
22.5°C in dark; vancomycin not measured using an assay noted to be stability indicating
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3475'>
3475
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefepime HCl
</para>
</entry>
<entry colname='col2'>
<para>
APO
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
NVP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Samples from 4-hr cefepime and 1-hr vancomycin infusions physically compatible during infusion and
after 24 hr at 22.5°C in dark. Cefepime chemically stable during infusion and after 12 hr at
22.5°C in dark; vancomycin not measured using an assay noted to be stability indicating
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3475'>
3475
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefiderocol sulfate tosylate
</para>
</entry>
<entry colname='col2'>
<para>
SHI
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
GLA
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually incompatible upon mixing
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3662'>
3662
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefiderocol sulfate tosylate
</para>
</entry>
<entry colname='col2'>
<para>
SHI
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
GLA
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Results of subvisual tests indicate the presence of cloudiness with white particles
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3662'>
3662
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
100 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
12.5, 25, 30, 50 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1721'>
1721
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
100 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
No precipitate visually observed over 7 days at room temperature, but nonvisible incompatibility
cannot be ruled out
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1721'>
1721
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
HO
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
HO
</para>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White cloudiness forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
HO
</para>
</entry>
<entry colname='col3'>
<para>
1 and 10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotaxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
HO
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 200
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotetan disodium
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms followed by white precipitate in 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotetan disodium
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
10 and 50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotetan disodium
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Subvisible haze forms immediately. White precipitate in 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefotetan disodium
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 200
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefoxitin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
180 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefoxitin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Immediate gross white precipitate
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefoxitin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visible haze forms in 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefoxitin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefoxitin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 180
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r873'>
873
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 200
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 200
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
125 mg/mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
30 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2434'>
2434
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para>
GSK
</para>
</entry>
<entry colname='col3'>
<para>
120 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
30 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2513'>
2513
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
125 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime–avibactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
FOR
</para>
</entry>
<entry colname='col3'>
<para>
8 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f29'>
<sup>
cc
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5, 10, 15, 20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime–avibactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
FOR
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f29'>
<sup>
cc
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 24 hr at room temperature with no loss of antimicrobial activity
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime–avibactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
FOR
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f29'>
<sup>
cc
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
10, 15, 20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime–avibactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
FOR
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f29'>
<sup>
cc
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5, 10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 24 hr at room temperature with no loss of antimicrobial activity
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftazidime–avibactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
FOR
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f29'>
<sup>
cc
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
15, 20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftolozane sulfate–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
CUB
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
<a href='#y-si-f24'>
<sup>
x
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3262'>
3262
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftolozane sulfate–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
15 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f24'>
<sup>
x
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5, 10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 24 hr at room temperature with no loss of antimicrobial activity
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftolozane sulfate–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
15 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f24'>
<sup>
x
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
15, 20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftriaxone sodium
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
100 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
White precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1398'>
1398
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftriaxone sodium
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
250 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftriaxone sodium
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
10 and 50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftriaxone sodium
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Subvisible haze forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ceftriaxone sodium
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 250
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefuroxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
150 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms followed by a subvisible haze
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefuroxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefuroxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Subvisible haze forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefuroxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cefuroxime sodium
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
, 150
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cisatracurium besylate
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
0.1, 2, 5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2074'>
2074
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Clarithromycin
</para>
</entry>
<entry colname='col2'>
<para>
AB
</para>
</entry>
<entry colname='col3'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
DB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 72 hr at both 30 and 17°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2174'>
2174
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
100 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3245'>
3245
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
0.8
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
and 1.25
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
0.3 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for up to 1 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
23.75 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
0.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for up to 1 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
1.25
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
and 1.75
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
0.6 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for up to 1 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
1.25
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
and 3.4
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
1.3 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for up to 1 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
0.8
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 1.75
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 3.4
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, and 6.8
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for up to 1 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
12.5
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
and 20
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
1.25 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
2.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms within 1 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
6.8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
2.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
1.25
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
and 12.5
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cloxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
SMX
</para>
</entry>
<entry colname='col3'>
<para>
1.25 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PPC
</para>
</entry>
<entry colname='col5'>
<para>
9.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White, gel-like precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3246'>
3246
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Colistimethate sodium
</para>
</entry>
<entry colname='col2'>
<para>
MIL
</para>
</entry>
<entry colname='col3'>
<para>
1.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
SIA
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 1 hr at 26°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3335'>
3335
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Cyclophosphamide
</para>
</entry>
<entry colname='col2'>
<para>
MJ
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1194'>
1194
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Defibrotide sodium
</para>
</entry>
<entry colname='col2'>
<para>
JAZ
</para>
</entry>
<entry colname='col3'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
MYL
</para>
</entry>
<entry colname='col5'>
<para>
10.4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Solution became milky white and opalescent. Precipitate formed within 1 hr when defibrotide added
to vancomycin HCl, but developed immediately when order of mixing was reversed
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3149'>
3149
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Dexmedetomidine HCl
</para>
</entry>
<entry colname='col2'>
<para>
AB
</para>
</entry>
<entry colname='col3'>
<para>
4 mcg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2383'>
2383
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Diltiazem HCl
</para>
</entry>
<entry colname='col2'>
<para>
MMD
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 and 50 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1807'>
1807
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Docetaxel
</para>
</entry>
<entry colname='col2'>
<para>
RPR
</para>
</entry>
<entry colname='col3'>
<para>
0.9 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2224'>
2224
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Doripenem
</para>
</entry>
<entry colname='col2'>
<para>
JJ
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2743'>
2743
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Doxapram HCl
</para>
</entry>
<entry colname='col2'>
<para>
RB
</para>
</entry>
<entry colname='col3'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2470'>
2470
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Doxorubicin HCl liposomal
</para>
</entry>
<entry colname='col2'>
<para>
SEQ
</para>
</entry>
<entry colname='col3'>
<para>
0.4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2087'>
2087
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Enalaprilat
</para>
</entry>
<entry colname='col2'>
<para>
MSD
</para>
</entry>
<entry colname='col3'>
<para>
0.05 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at room temperature under fluorescent light
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1355'>
1355
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Eravacycline dihydrochloride
</para>
</entry>
<entry colname='col2'>
<para>
TET
</para>
</entry>
<entry colname='col3'>
<para>
0.6 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AVG
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3532'>
3532
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Esmolol HCl
</para>
</entry>
<entry colname='col2'>
<para>
DCC
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1169'>
1169
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Etoposide phosphate
</para>
</entry>
<entry colname='col2'>
<para>
BR
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2218'>
2218
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Fat emulsion, intravenous
</para>
</entry>
<entry colname='col2'>
<para>
OTS
</para>
</entry>
<entry colname='col3'>
<para>
20%
<a href='#y-si-f25'>
<sup>
y
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
SHI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f26'>
<sup>
z
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Fine particles increased after preparation and continued to increase over time
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3452'>
3452
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Fenoldopam mesylate
</para>
</entry>
<entry colname='col2'>
<para>
AB
</para>
</entry>
<entry colname='col3'>
<para>
80 mcg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2467'>
2467
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Filgrastim
</para>
</entry>
<entry colname='col2'>
<para>
AMG
</para>
</entry>
<entry colname='col3'>
<para>
30 mcg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1687'>
1687
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Floxacillin
<a href='#y-si-f30'>
<sup>
dd
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
250 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Fluconazole
</para>
</entry>
<entry colname='col2'>
<para>
RR
</para>
</entry>
<entry colname='col3'>
<para>
2 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LY
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1407'>
1407
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Fludarabine phosphate
</para>
</entry>
<entry colname='col2'>
<para>
BX
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1439'>
1439
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Foscarnet sodium
</para>
</entry>
<entry colname='col2'>
<para>
AST
</para>
</entry>
<entry colname='col3'>
<para>
24 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1335'>
1335
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Foscarnet sodium
</para>
</entry>
<entry colname='col2'>
<para>
AST
</para>
</entry>
<entry colname='col3'>
<para>
24 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
15 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 25°C under fluorescent light
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1393'>
1393
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Foscarnet sodium
</para>
</entry>
<entry colname='col2'>
<para>
AST
</para>
</entry>
<entry colname='col3'>
<para>
24 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at room temperature. No precipitate found
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2063'>
2063
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Furosemide
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Gallium nitrate
</para>
</entry>
<entry colname='col2'>
<para>
FUJ
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1673'>
1673
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Gemcitabine HCl
</para>
</entry>
<entry colname='col2'>
<para>
LI
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2226'>
2226
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Granisetron HCl
</para>
</entry>
<entry colname='col2'>
<para>
SKB
</para>
</entry>
<entry colname='col3'>
<para>
0.05 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2000'>
2000
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
TR
</para>
</entry>
<entry colname='col3'>
<para>
50 units/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
6.6 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually incompatible within 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1793'>
1793
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
ES
</para>
</entry>
<entry colname='col3'>
<para>
100 units/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2063'>
2063
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
LEO
</para>
</entry>
<entry colname='col3'>
<para>
10 and 5000 units/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PHS
</para>
</entry>
<entry colname='col5'>
<para>
2.5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible with little change in heparin activity in 14 days at 4 and 37°C.
Antibiotic not tested
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2684'>
2684
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Heparin sodium
</para>
</entry>
<entry colname='col2'>
<para>
LEO
</para>
</entry>
<entry colname='col3'>
<para>
10 units/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
PHS
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible with little change in heparin activity in 14 days at 4 and 37°C.
Antibiotic not tested
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2684'>
2684
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Hetastarch in lactated electrolyte
</para>
</entry>
<entry colname='col2'>
<para>
AB
</para>
</entry>
<entry colname='col3'>
<para>
6%
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2339'>
2339
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Hydromorphone HCl
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
0.2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r987'>
987
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Hydromorphone HCl
</para>
</entry>
<entry colname='col2'>
<para>
HOS
</para>
</entry>
<entry colname='col3'>
<para>
2 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2794'>
2794
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ibuprofen lysinate
</para>
</entry>
<entry colname='col2'>
<para>
OVA
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Measured turbidity increased immediately and solution became milky white and opaque
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3541'>
3541
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Idarubicin HCl
</para>
</entry>
<entry colname='col2'>
<para>
AD
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AD
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Color changes immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1525'>
1525
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Imipenem–cilastatin sodium–relebactam
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
<a href='#y-si-f33'>
<sup>
gg
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
SZ
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr at 20 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3604'>
3604
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Insulin, regular
</para>
</entry>
<entry colname='col2'>
<para>
LI
</para>
</entry>
<entry colname='col3'>
<para>
0.2 unit/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1395'>
1395
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Isavuconazonium sulfate
</para>
</entry>
<entry colname='col2'>
<para>
ASP
</para>
</entry>
<entry colname='col3'>
<para>
1.5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3263'>
3263
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Labetalol HCl
</para>
</entry>
<entry colname='col2'>
<para>
SC
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 18°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1171'>
1171
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Levofloxacin
</para>
</entry>
<entry colname='col2'>
<para>
OMN
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 24°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2233'>
2233
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Linezolid
</para>
</entry>
<entry colname='col2'>
<para>
PHU
</para>
</entry>
<entry colname='col3'>
<para>
2 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
FUJ
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2264'>
2264
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Lorazepam
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
0.33 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1855'>
1855
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Magnesium sulfate
</para>
</entry>
<entry colname='col2'>
<para>
IX
</para>
</entry>
<entry colname='col3'>
<para>
16.7, 33.3, 66.7, 100 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for at least 4 hr at 32°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r813'>
813
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Melphalan HCl
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
0.1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LY
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 3 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1557'>
1557
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Meperidine HCl
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r987'>
987
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Meropenem
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
</para>
</entry>
<entry colname='col3'>
<para>
1 and 50 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1994'>
1994
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Meropenem
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
SZ
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3538'>
3538
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Meropenem–vaborbactam
</para>
</entry>
<entry colname='col2'>
<para>
TMC
</para>
</entry>
<entry colname='col3'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f22'>
<sup>
v
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
FRK
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 3 hr at 20 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3380'>
3380
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Methotrexate sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
</para>
</entry>
<entry colname='col3'>
<para>
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f6'>
<sup>
f
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
510 mg
<a href='#y-si-f7'>
<sup>
g
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible during 1-hr simultaneous infusion
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1405'>
1405
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Methotrexate sodium
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
30 mg/mL
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 2 hr at room temperature. Yellow precipitate in 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1788'>
1788
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Methylprednisolone
<a href='#y-si-f30'>
<sup>
dd
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Midazolam HCl
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1847'>
1847
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Midazolam HCl
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
5 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1855'>
1855
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Milrinone lactate
</para>
</entry>
<entry colname='col2'>
<para>
SS
</para>
</entry>
<entry colname='col3'>
<para>
0.2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
OR
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2381'>
2381
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Morphine sulfate
</para>
</entry>
<entry colname='col2'>
<para>
WI
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r987'>
987
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Mycophenolate mofetil HCl
</para>
</entry>
<entry colname='col2'>
<para>
RC
</para>
</entry>
<entry colname='col3'>
<para>
5.9 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible and 3% mycophenolate mofetil loss in 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2738'>
2738
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nafcillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
BE
</para>
</entry>
<entry colname='col3'>
<para>
250 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms followed by a visibly hazy solution
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nafcillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
BE
</para>
</entry>
<entry colname='col3'>
<para>
10 and 50 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nafcillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
BE
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nafcillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
BE
</para>
</entry>
<entry colname='col3'>
<para>
10
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 50
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
, 250
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Subvisible measured haze forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nafcillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
BE
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Nicardipine HCl
</para>
</entry>
<entry colname='col2'>
<para>
DCC
</para>
</entry>
<entry colname='col3'>
<para>
0.1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LE
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r235'>
235
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Ondansetron HCl
</para>
</entry>
<entry colname='col2'>
<para>
GL
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1365'>
1365
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Oxacillin sodium
</para>
</entry>
<entry colname='col2'>
<para>
AUR
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Precipitates immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3477'>
3477
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Paclitaxel
</para>
</entry>
<entry colname='col2'>
<para>
NCI
</para>
</entry>
<entry colname='col3'>
<para>
1.2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1528'>
1528
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Palonosetron HCl
</para>
</entry>
<entry colname='col2'>
<para>
MGI
</para>
</entry>
<entry colname='col3'>
<para>
50 mcg/mL
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible and no loss of either drug in 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2765'>
2765
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Pancuronium bromide
</para>
</entry>
<entry colname='col2'>
<para>
ES
</para>
</entry>
<entry colname='col3'>
<para>
0.05 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
ES
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 28°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1337'>
1337
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Pantoprazole sodium
</para>
</entry>
<entry colname='col2'>
<para>
ALT
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
8 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
ME
</para>
</entry>
<entry colname='col5'>
<para>
40 mg/mL
</para>
</entry>
<entry colname='col6'>
<para>
Color change after 10 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2727'>
2727
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Pemetrexed disodium
</para>
</entry>
<entry colname='col2'>
<para>
LI
</para>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2564'>
2564
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Phenytoin
<a href='#y-si-f30'>
<sup>
dd
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
50 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White turbidity forms immediately and white precipitate forms in 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1688'>
1688
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
10 and 50 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Gross white precipitate forms immediately
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
LE
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
1
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
, 10
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
, 50
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
, 200
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2189'>
2189
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
SZ
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
<a href='#y-si-f23'>
<sup>
w
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 5 days at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2935'>
2935
</a>
</sup>
,
<sup>
<a href='a586999.xml#r3474'>
3474
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
SZ
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
<a href='#y-si-f23'>
<sup>
w
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 5 days at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2935'>
2935
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
100 mg/mL
<a href='#y-si-f4'>
<sup>
d
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient precipitate clears within 15 seconds
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2933'>
2933
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
16, 30, 40, 80, 100 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
2 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
16, 30, 40 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
80, 100 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White precipitate forms only when piperacillin–tazobactam added to vancomycin; not observed
when order of mixing was reversed
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
16, 30, 40, 80, 100 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
16 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Persistent white precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 80, 100 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Immediate white cloudiness forms, then dissipates
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
16, 30 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
40 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
White precipitate forms only when piperacillin–tazobactam added to vancomycin; not observed
when order of mixing was reversed
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
APP
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
80, 100 mg
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Immediate white cloudiness forms, then dissipates
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3476'>
3476
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
4 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
60 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5, 8, 9 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
WY
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 53.3, 80 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
6 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
7 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient and reversible precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
WY
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 53.3, 80 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Transient and reversible precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
HOS
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 40, 44.4, 53.3, 60, 71.1, 80 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
APP
</para>
</entry>
<entry colname='col5'>
<para>
12 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Irreversible precipitate forms
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
60 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
BA
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
WY
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
30, 53.3, 80 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
BA
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 21 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3478'>
3478
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
SZ
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
28 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 24 hr at room temperature with no loss of antimicrobial activity
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
SZ
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
28 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
10, 15, 20 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3480'>
3480
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin sodium–tazobactam sodium
</para>
</entry>
<entry colname='col2'>
<para>
PF
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
60 mg/mL
<a href='#y-si-f21'>
<sup>
u
</sup>
</a>
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
BA
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f28'>
<sup>
bb
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
No evidence of physical incompatibility via simulated Y-site infusion; however, a white
precipitate forms during actual Y-site infusion
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3481'>
3481
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
?
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Piperacillin–tazobactam
<a href='#y-si-f30'>
<sup>
dd
</sup>
</a>
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#y-si-f31'>
<sup>
ee
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
200 mg/mL
<a href='#y-si-f32'>
<sup>
ff
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Plazomicin sulfate
</para>
</entry>
<entry colname='col2'>
<para>
ACH
</para>
</entry>
<entry colname='col3'>
<para>
24 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
FRK
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 1 hr at 20 to 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3432'>
3432
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Posaconazole
</para>
</entry>
<entry colname='col2'>
<para>
ME
</para>
</entry>
<entry colname='col3'>
<para>
18 mg/mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2911'>
2911
</a>
</sup>
,
<sup>
<a href='a586999.xml#r2912'>
2912
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Propofol
</para>
</entry>
<entry colname='col2'>
<para>
ZEN
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 1 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2066'>
2066
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Propofol
</para>
</entry>
<entry colname='col2'>
<para>
BA
<a href='#y-si-f18'>
<sup>
r
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Emulsion disruption within 1 to 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2336'>
2336
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Propofol
</para>
</entry>
<entry colname='col2'>
<para>
ASZ
<a href='#y-si-f27'>
<sup>
aa
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
10 mg/mL
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for up to 30 days at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2336'>
2336
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Propofol
</para>
</entry>
<entry colname='col2'>
<para>
<a href='#y-si-f31'>
<sup>
ee
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Remifentanil HCl
</para>
</entry>
<entry colname='col2'>
<para>
GW
</para>
</entry>
<entry colname='col3'>
<para>
0.025 and 0.25 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2075'>
2075
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sargramostim
</para>
</entry>
<entry colname='col2'>
<para>
IMM
</para>
</entry>
<entry colname='col3'>
<para>
10 mcg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1436'>
1436
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sargramostim
</para>
</entry>
<entry colname='col2'>
<para>
IMM
</para>
</entry>
<entry colname='col3'>
<para>
15 mcg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 2 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1618'>
1618
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sargramostim
</para>
</entry>
<entry colname='col2'>
<para>
IMM
</para>
</entry>
<entry colname='col3'>
<para>
6 mcg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
<a href='#y-si-f8'>
<sup>
h
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
20 mg/mL
<a href='#y-si-f3'>
<sup>
c
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Haze forms within 15 min and increases due to vancomycin incompatibility with albumin human
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1618'>
1618
</a>
</sup>
,
<sup>
<a href='a586999.xml#r1701'>
1701
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Sodium bicarbonate
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
1.4%
</para>
</entry>
<entry colname='col4'/>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at room temperature
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1788'>
1788
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Tacrolimus
</para>
</entry>
<entry colname='col2'>
<para>
FUJ
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1630'>
1630
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Tedizolid phosphate
</para>
</entry>
<entry colname='col2'>
<para>
CUB
</para>
</entry>
<entry colname='col3'>
<para>
0.8 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
HOS
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 2 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3244'>
3244
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Teniposide
</para>
</entry>
<entry colname='col2'>
<para>
BR
</para>
</entry>
<entry colname='col3'>
<para>
0.1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1725'>
1725
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Theophylline
</para>
</entry>
<entry colname='col2'>
<para>
TR
</para>
</entry>
<entry colname='col3'>
<para>
4 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
6.6 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 6 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1793'>
1793
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Theophylline
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
20 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Thiotepa
</para>
</entry>
<entry colname='col2'>
<para>
IMM
<a href='#y-si-f9'>
<sup>
i
</sup>
</a>
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1861'>
1861
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Tigecycline
</para>
</entry>
<entry colname='col2'>
<para>
WY
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para/>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2714'>
2714
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TNA #218 to #226
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'/>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2215'>
2215
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #61
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
<a href='#y-si-f11'>
<sup>
k
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
50 mg/1 mL
<a href='#y-si-f12'>
<sup>
l
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1012'>
1012
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #61
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
<a href='#y-si-f13'>
<sup>
m
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
300 mg/6 mL
<a href='#y-si-f12'>
<sup>
l
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1012'>
1012
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #91
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'>
<para>
<a href='#y-si-f14'>
<sup>
n
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
30 mg
<a href='#y-si-f15'>
<sup>
o
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1170'>
1170
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #189
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'/>
<entry colname='col4'>
<para>
DB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Visually compatible for 24 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1767'>
1767
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
TPN #212 to #215
<a href='#y-si-f10'>
<sup>
j
</sup>
</a>
</para>
</entry>
<entry colname='col2'/>
<entry colname='col3'/>
<entry colname='col4'>
<para>
AB
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 23°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r2109'>
2109
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Valproate sodium
</para>
</entry>
<entry colname='col2'>
<para/>
</entry>
<entry colname='col3'>
<para>
100 mg/mL
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically incompatible
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r3536'>
3536
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
I
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Vecuronium bromide
</para>
</entry>
<entry colname='col2'>
<para>
OR
</para>
</entry>
<entry colname='col3'>
<para>
0.1 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
ES
</para>
</entry>
<entry colname='col5'>
<para>
5 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 24 hr at 28°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1337'>
1337
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Vinorelbine tartrate
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
1 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LY
</para>
</entry>
<entry colname='col5'>
<para>
10 mg/mL
<a href='#y-si-f2'>
<sup>
b
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 22°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1558'>
1558
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
<row valign='top'>
<entry colname='col1'>
<para>
Zidovudine
</para>
</entry>
<entry colname='col2'>
<para>
BW
</para>
</entry>
<entry colname='col3'>
<para>
4 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col4'>
<para>
LI
</para>
</entry>
<entry colname='col5'>
<para>
15 mg/mL
<a href='#y-si-f1'>
<sup>
a
</sup>
</a>
</para>
</entry>
<entry colname='col6'>
<para>
Physically compatible for 4 hr at 25°C
</para>
</entry>
<entry colname='col7'>
<para>
<sup>
<a href='a586999.xml#r1193'>
1193
</a>
</sup>
</para>
</entry>
<entry colname='col8'>
<para>
C
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
<table frame='bottom'>
<tgroup cols='1' colsep='0' rowsep='0' align='left'>
<colspec colnum='1' colname='col1' colwidth='*'/>
<tbody>
<row valign='top'>
<entry colname='col1'>
<para>
<a name='y-si-f1'/>
<sup>
a
</sup>
Tested in dextrose 5%.
</para>
<para>
<a name='y-si-f2'/>
<sup>
b
</sup>
Tested in sodium chloride 0.9%.
</para>
<para>
<a name='y-si-f3'/>
<sup>
c
</sup>
Tested in both dextrose 5% and sodium chloride 0.9%.
</para>
<para>
<a name='y-si-f4'/>
<sup>
d
</sup>
Tested in sterile water for injection.
</para>
<para>
<a name='y-si-f5'/>
<sup>
e
</sup>
Tested in a 1:1 mixture of dextrose 5% and TPN #274 (see Appendix).
</para>
<para>
<a name='y-si-f6'/>
<sup>
f
</sup>
Concentration unspecified.
</para>
<para>
<a name='y-si-f7'/>
<sup>
g
</sup>
Infused over one hour simultaneously with methotrexate.
</para>
<para>
<a name='y-si-f8'/>
<sup>
h
</sup>
Tested with 0.1% albumin human added.
</para>
<para>
<a name='y-si-f9'/>
<sup>
i
</sup>
Lyophilized formulation tested.
</para>
<para>
<a name='y-si-f10'/>
<sup>
j
</sup>
Refer to Appendix for the composition of parenteral nutrition solutions. TNA indicates a 3-in-1
admixture, and TPN indicates a 2-in-1 admixture.
</para>
<para>
<a name='y-si-f11'/>
<sup>
k
</sup>
Run at 21 mL/hr.
</para>
<para>
<a name='y-si-f12'/>
<sup>
l
</sup>
Given over 30 minutes by syringe pump.
</para>
<para>
<a name='y-si-f13'/>
<sup>
m
</sup>
Run at 94 mL/hr.
</para>
<para>
<a name='y-si-f14'/>
<sup>
n
</sup>
Run at 10 mL/hr.
</para>
<para>
<a name='y-si-f15'/>
<sup>
o
</sup>
Given over one hour by syringe pump.
</para>
<para>
<a name='y-si-f16'/>
<sup>
p
</sup>
Tested in a 1:1 mixture of (1) dextrose 5% and dextrose 5% in sodium chloride 0.45% with and
without potassium chloride 20 mEq/L and also in (2) dextrose 10% in sodium chloride 0.45% with and
without potassium chloride 20 mEq/L.
</para>
<para>
<a name='y-si-f17'/>
<sup>
q
</sup>
Tested with albumin human 0.1%.
</para>
<para>
<a name='y-si-f18'/>
<sup>
r
</sup>
Test performed using the formulation WITHOUT edetate disodium.
</para>
<para>
<a name='y-si-f19'/>
<sup>
s
</sup>
Tested in either dextrose 5% or in sodium chloride 0.9%, but the report did not specify which
solution.
</para>
<para>
<a name='y-si-f20'/>
<sup>
t
</sup>
Ampicillin component. Ampicillin in a 2:1 fixed-ratio concentration with sulbactam.
</para>
<para>
<a name='y-si-f21'/>
<sup>
u
</sup>
Piperacillin component. Piperacillin in an 8:1 fixed-ratio concentration with tazobactam.
</para>
<para>
<a name='y-si-f22'/>
<sup>
v
</sup>
Meropenem component. Meropenem in a 1:1 fixed-ratio concentration with vaborbactam.
</para>
<para>
<a name='y-si-f23'/>
<sup>
w
</sup>
If sterile water for injection is used as the diluent, manufacturers recommend a maximum volume
per dose of 50 mL.
</para>
<para>
<a name='y-si-f24'/>
<sup>
x
</sup>
Ceftolozane component. Ceftolozane in a 2:1 fixed-ratio concentration with tazobactam.
</para>
<para>
<a name='y-si-f25'/>
<sup>
y
</sup>
Run at 25 mL/hr with dextrose 5% run at 83 mL/hr.
</para>
<para>
<a name='y-si-f26'/>
<sup>
z
</sup>
Run at 100 mL/hr.
</para>
<para>
<a name='y-si-f27'/>
<sup>
aa
</sup>
Test performed using the formulation WITH edetate disodium.
</para>
<para>
<a name='y-si-f28'/>
<sup>
bb
</sup>
Tested as the premixed infusion solution.
</para>
<para>
<a name='y-si-f29'/>
<sup>
cc
</sup>
Ceftazidime component. Ceftazidime in a 4:1 fixed-ratio concentration with avibactam.
</para>
<para>
<a name='y-si-f30'/>
<sup>
dd
</sup>
Salt not specified.
</para>
<para>
<a name='y-si-f31'/>
<sup>
ee
</sup>
Presence or absence of edetate disodium not specified.
</para>
<para>
<a name='y-si-f32'/>
<sup>
ff
</sup>
Not specified whether concentration refers to single component or combined components.
</para>
<para>
<a name='y-si-f33'/>
<sup>
gg
</sup>
Imipenem component. Imipenem in a 2:2:1 fixed-ratio concentration with cilstatin and relebactam.
</para>
</entry>
</row>
</tbody>
</tgroup>
</table>
</y-site-inj-compat>
</compatibility>
<additional-compat-info>
<head class='a-head'>
Additional Compatibility Information
</head>
<sect>
<head class='b-head'>
Peritoneal Dialysis Solutions
</head>
<para>
Reports have revealed that administration of sterile vancomycin by the intraperitoneal route during
continuous ambulatory peritoneal dialysis (CAPD) has resulted in a syndrome of chemical peritonitis, ranging
from a cloudy dialysate alone to a cloudy dialysate accompanied by variable degrees of abdominal pain and
fever.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
Manufacturers state that the safety and efficacy of vancomycin administered by the intraperitoneal route
have not been established by adequate and well-controlled trials.
<sup>
<a href='a586999.xml#r3464'>
3464
</a>
</sup>
<sup>
<a href='a586999.xml#r3465'>
3465
</a>
</sup>
<sup>
<a href='a586999.xml#r3466'>
3466
</a>
</sup>
<sup>
<a href='a586999.xml#r3467'>
3467
</a>
</sup>
<sup>
<a href='a586999.xml#r3468'>
3468
</a>
</sup>
<sup>
<a href='a586999.xml#r3469'>
3469
</a>
</sup>
</para>
<para>
The activity of vancomycin 15 mg/L was evaluated in peritoneal dialysis fluids containing dextrose 1.5 or
4.25% (Dianeal 137, Travenol). Storage at 25°C resulted in virtually no loss of antimicrobial activity
in 24 hours.
<sup>
<a href='a586999.xml#r515'>
515
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lilly) prepared at vancomycin concentrations of 10 and 50 mg/L in peritoneal
dialysis concentrate with dextrose 50% (McGaw) retained 93 to 100% of its initial activity after 24 hours of
storage at room temperature.
<sup>
<a href='a586999.xml#r1044'>
1044
</a>
</sup>
</para>
<para>
The stability of vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 20 mg/L in
peritoneal dialysis solutions (Dianeal 137 and PD-2) with heparin sodium 500 units/L was evaluated.
Approximately 95 ± 12% activity remained after 24 hours at 25°C.
<sup>
<a href='a586999.xml#r1228'>
1228
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 15 mg/L to 5.3 g/L in Dianeal
with dextrose 2.5 or 4.25% was physically compatible with heparin sodium (Organon) 500 to 14,300 units/L for
24 hours at 25°C under fluorescent light. However, a white precipitate formed immediately in
combinations of heparin sodium with vancomycin hydrochloride 6.9 to 14.3 g/L.
<sup>
<a href='a586999.xml#r1322'>
1322
</a>
</sup>
</para>
<para>
The retention of antimicrobial activity of vancomycin hydrochloride (Lilly) prepared at a vancomycin
concentration of 1 g/L alone and with each of two aminoglycosides, gentamicin sulfate (SoloPak) prepared at
a gentamicin concentration of 120 mg/L and tobramycin sulfate (Lilly) prepared at a tobramycin concentration
of 120 mg/L, in Dianeal PD-2 (Travenol) with dextrose 1.5% was evaluated. Little or no loss of any
antibiotic occurred in 8 hours at 37°C. Vancomycin hydrochloride alone retained activity for at least
48 hours at 4 and 25°C. In combination with gentamicin sulfate and tobramycin sulfate, antimicrobial
activity of both vancomycin and the aminoglycosides was retained for up to 48 hours. However, refrigeration
at 4°C was recommended for storage periods greater than 24 hours.
<sup>
<a href='a586999.xml#r1414'>
1414
</a>
</sup>
</para>
<para>
The stability of vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 25 mg/L in
Dianeal 137 (Baxter) with dextrose 1.36 and 3.86%, while protected from direct sunlight, was evaluated. At
both dextrose concentrations, less than 4% vancomycin was lost in 42 days at 4°C. At 20°C, a 5% or
less loss occurred in 28 days. At 37°C, a 10% loss occurred in 6 to 7 days.
<sup>
<a href='a586999.xml#r1654'>
1654
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 1 mg/mL admixed with ceftazidime
(Lilly) 0.5 mg/mL in Dianeal PD-2 (Baxter) with 1.5% and also 4.25% dextrose was evaluated for compatibility
and stability. Samples were stored under fluorescent light at 4 and 24°C for 24 hours and at 37°C
for 12 hours. No precipitation or other change was observed by visual inspection in any sample. No loss of
either drug was found in the samples stored at 4°C and no loss of vancomycin and about 4 to 5%
ceftazidime loss were found in the samples stored at 24°C in 24 hours. Vancomycin losses of 3% or less
and ceftazidime loss of about 6% were found in the samples stored at 37°C for 12 hours. No difference
in stability was found between samples at either dextrose concentration.
<sup>
<a href='a586999.xml#r2217'>
2217
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lederle) prepared at a vancomycin concentration of 0.05 mg/mL in Dianeal PD-2 with
dextrose 1.5% with or without heparin sodium 1 unit/mL in PVC bags was chemically stable for up to 6 days at
4°C (about 3 to 5% loss) and 25°C (up to 7% loss) and 5 days at body temperature of 37°C.
<sup>
<a href='a586999.xml#r866'>
866
</a>
</sup>
</para>
<para>
The addition of ceftazidime (Glaxo) 0.1 mg/mL to this peritoneal dialysis solution demonstrated a somewhat
reduced stability with the ceftazidime being the defining component. The ceftazidime was chemically stable
for up to 6 days at 4°C (about 3% loss), 3 days at 25°C (about 9 to 10% loss), and 12 hours at
body temperature of 37°C with the vancomycin exhibiting less loss throughout.
<sup>
<a href='a586999.xml#r866'>
866
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lederle) prepared at a vancomycin concentration of 25 mcg/mL in Delflex peritoneal
dialysis solution bags with 2.5% dextrose (Fresenius) was stable with little loss occurring in 14 days
refrigerated and at room temperature.
<sup>
<a href='a586999.xml#r2573'>
2573
</a>
</sup>
</para>
<para>
Gentamicin sulfate (American Pharmaceutical Partners) prepared at a gentamicin concentration of 8 mcg/mL
with vancomycin hydrochloride (Lederle) prepared at a vancomycin concentration of 25 mcg/mL in Delflex
peritoneal dialysis solution bags with 2.5% dextrose (Fresenius) was stable with little or no loss of either
drug occurring in 14 days refrigerated and at room temperature.
<sup>
<a href='a586999.xml#r2573'>
2573
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Abbott) prepared at a vancomycin concentration of 1 mg/mL in icodextrin 7.5% PD
(Baxter) was tested for stability at 5, 24, and 37°C. The solutions remained clear and colorless.
Little or no loss at 5°C and about 3% loss at 24°C after 7 days of storage was found. At
37°C, about 6% loss occurred in 24 hours.
<sup>
<a href='a586999.xml#r2650'>
2650
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Hospira) prepared at a vancomycin concentration of 1 g/L in Extraneal with
icodextrin 7.5% (Baxter) peritoneal dialysis solution bags exhibited less than 10% loss in 14 days at 25 and
4°C and 2 days at 37°C.
<sup>
<a href='a586999.xml#r3537'>
3537
</a>
</sup>
Vancomycin hydrochloride (Hospira) prepared at a vancomycin concentration of 1 g/L with gentamicin sulfate
(Pfizer) prepared at a gentamicin concentration of 20 mg/L in Extraneal with icodextrin 7.5% (Baxter)
peritoneal dialysis solution bags exhibited less than 10% loss of either drug in 14 days at 25 and 4°C
and 7% loss of vancomycin and 3% loss of gentamicin in 4 days at 37°C.
<sup>
<a href='a586999.xml#r3537'>
3537
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Heparin Locks
</head>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 25 mcg/mL and heparin sodium
(Elkins-Sinn) 100 units/mL in sodium chloride 0.9% as a catheter flush solution were evaluated for stability
when stored at 4°C for 14 days. The flush solution was visually clear, and the vancomycin activity and
heparin activity were retained throughout the storage period. However, an additional 24 hours at 37°C
to simulate use conditions resulted in losses of both agents ranging from 20 to 37%.
<sup>
<a href='a586999.xml#r1933'>
1933
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride (Lilly) prepared at a vancomycin concentration of 25 mcg/mL and preservative-free
heparin sodium (Elkins-Sinn) 100 units/mL in sodium chloride 0.9% in 2-mL glass vials for use as a central
catheter flush solution were evaluated for compatibility and stability at 4 and 28°C. Visual inspection
found no evidence of color change or particulate formation throughout the study. Heparin activity remained
unchanged for 100 days. Acceptable vancomycin levels were maintained for 30 days at 28°C and for 63
days at 4°C. However, unacceptable losses occurred after those times. The activity of both drugs was
unaffected by the presence of the other when compared to the activity of single drug controls.
<sup>
<a href='a586999.xml#r2542'>
2542
</a>
</sup>
</para>
<para>
Vancomycin hydrochloride prepared at a vancomycin concentration of 25 mcg/mL combined with heparin sodium
(Hospira) 10 units/mL in sterile water for injection for use as a lock solution was found to be physically
compatible. Little or no vancomycin loss occurred in 3 days at 4°C. However, losses of 8% occurred in 3
days at 27°C and 1 day at 40°C.
<sup>
<a href='a586999.xml#r2820'>
2820
</a>
</sup>
When ciprofloxacin (Sicor) 2 mg/mL was added to this flush solution, a white precipitate appeared within 1
day. Losses of both ciprofloxacin and vancomycin occurred as well.
<sup>
<a href='a586999.xml#r2820'>
2820
</a>
</sup>
</para>
</sect>
<sect>
<head class='b-head'>
Sodium Citrate Locks
</head>
<para>
The physical compatibility of catheter lock solutions prepared with sodium citrate 4% anticoagulant solution
(Baxter) and vancomycin (manufacturer unspecified) 5, 10, and 20 mg/mL was evaluated.
<sup>
<a href='a586999.xml#r3482'>
3482
</a>
</sup>
Solutions were stored 22 to 23°C and at 37°C in a water bath, both exposed to light and in the
dark.
<sup>
<a href='a586999.xml#r3482'>
3482
</a>
</sup>
No evidence of physical incompatibility was observed throughout the 48-hour study period in admixtures of
sodium citrate with vancomycin concentrations of 5 and 10 mg/mL.
<sup>
<a href='a586999.xml#r3482'>
3482
</a>
</sup>
However, admixtures containing sodium citrate and vancomycin 20 mg/mL demonstrated spectrophotometric
evidence of incompatibility in each of the 4 storage conditions, with demonstrated turbidity as assessed by
absorbance.
<sup>
<a href='a586999.xml#r3482'>
3482
</a>
</sup>
</para>
<para>
The physical compatibility, chemical stability, and antimicrobial activity of catheter lock solutions
prepared with sodium citrate 4% anticoagulant solution (Fenwal) combined with vancomycin (manufacturer
unspecified) 5 and 10 mg/mL and either gentamicin (Hospira) 1 mg/mL or ethanol 40% (v/v) were evaluated.
<sup>
<a href='a586999.xml#r3473'>
3473
</a>
</sup>
<sup>
<a href='a586999.xml#r3483'>
3483
</a>
</sup>
Solutions were stored at 25 and 37°C, both with and without light.
<sup>
<a href='a586999.xml#r3473'>
3473
</a>
</sup>
All solutions remained visually clear and demonstrated mean pH changes of 0.1 or less from baseline at 72
hours, with the exception of the admixture containing sodium citrate 4% with vancomycin 5 mg/mL and ethanol
40%, which developed slight turbidity after 48 hours in all 4 storage conditions.
<sup>
<a href='a586999.xml#r3473'>
3473
</a>
</sup>
Spectrophotometric evaluation demonstrated mean gentamicin and vancomycin concentrations in the range of 95
to 105% of initial concentrations at 72 hours; similarly, antimicrobial activity of gentamicin and
vancomycin at 72 hours was calculated to range between 95 and 106% of baseline based on disk diffusion
methodology.
<sup>
<a href='a586999.xml#r3473'>
3473
</a>
</sup>
</para>
</sect>
</additional-compat-info>
<copyright>
<para>
ASHP
<sup>
®
</sup>
Injectable Drug Information
<sup>
TM
</sup>
. Selected Revisions November 2, 2021. © Copyright, 2021. American Society of Health-System Pharmacists
<sup>
®
</sup>
, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.
</para>
</copyright>
<refs>
<head class='a-head'>
References
</head>
<para>
<xref-external href='a586999.xml'>
For a list of references cited in the text of this monograph, search the monograph titled
<ital>
References
</ital>
.
</xref-external>
</para>
</refs>
</hid-mono>
</hid>
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