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Disease Prioritization Data Package

This package has 16 modules. The Contraindications Module has 5 tables. Preview the first five rows of each table or Explore the schema

Contraindications Module

5 Tables

Each contraindication describes a case in which the drug is contraindicated. Each field adds a criteria to the contraindication, and if all of these are fulfilled, the contraindication applies. Structured contraindications are extracted from the contraindications section of drug product labels.

Contraindication Attributes

Contraindications can have additional relevant attributes represented in this table. Each row captures a value and a relationship (such as lab_value, route, age_group, etc.).The condition_id column always refers to the preferred version of a condition.

contraindication_id
relationship
value
00192333-2a0d-448c-be96-d6daee2c1921
dose_form
Capsule
00192333-2a0d-448c-be96-d6daee2c1921
dose_form
Suppository
00192333-2a0d-448c-be96-d6daee2c1921
dose_form
Suspension
00192333-2a0d-448c-be96-d6daee2c1921
route
Oral
00192333-2a0d-448c-be96-d6daee2c1921
route
Rectal
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Contraindication Categories

Certain contraindications are specific to combinations of categories of drugs, and this is represented in this table (coadmin indicates if the contraindication is specific to coadministration of the contraindication drug and the related category).

contraindication_id
category_id
coadmin
00e76f16-a2c5-4518-9ec5-069bf660283b
452
0
024fef09-ac66-4b88-ae17-bab430bfe842
2647
1
02530adb-a23f-4a12-90e7-c62b9d00031b
641
1
02ebca63-d80c-475a-aa26-2bfc1b90fd59
2649
0
035da84c-f2b1-419c-a7f7-35f992892b43
1004
1
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Contraindication Conditions

Contraindications are linked to multiple DrugBank conditions, such as prerequisite therapies and patient diseases and conditions.

contraindication_id
condition_id
relationship
4d0a3ac4-ab95-43b0-83fc-46b045d53704
193
patient_condition
4dec41d3-00e5-40e1-80b9-9ce2ecbb39f4
214
patient_condition
65c108b0-7801-40d5-af53-2308b860b320
288
patient_condition
ea5866e5-2531-45cf-8565-4c1d7dd20879
471
patient_condition
5627f902-94fe-4a1d-9c7e-c7633e091d97
480
patient_condition
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Contraindication Drugs

Each row in this table describes certain contraindications that are specific to combinations of drugs.

contraindication_id
drug_id
coadmin
00065312-b025-437b-80ed-122cbd76ba77
9058
0
001fbd7c-7bf3-4a0c-8e9f-d1893d0bab56
798
0
0028e032-5558-4b84-a99f-645cc6daad01
977
0
0196c017-6b47-45d2-8227-c0c1a667c3ef
18588
0
01a43d53-0e68-49e0-b951-48be39f70cc3
1026
1
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Structured Contraindications

Each row in this table describes a case in which a drug (referenced by the drug_id column) is contraindicated based on the given criteria fields (demographics, region, and time period).

id
drug_id
region
time_period
sex_group
min_age_amount
min_age_unit
max_age_amount
max_age_unit
00065312-b025-437b-80ed-122cbd76ba77
331
US
00192333-2a0d-448c-be96-d6daee2c1921
328
US
0019e472-060a-4480-ae48-5fbd81f57857
9191
Italy
0019ff5a-e653-40b8-90be-1089ac00fd3f
18728
Italy
001fbd7c-7bf3-4a0c-8e9f-d1893d0bab56
22368
Austria
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Showing 5 of 5 tables